The Sixth International Meeting of Andrology was held in Rome, Italy, on June 2-3, 1995 at the Pontificia Universita Urbaniana, the principal university of the Vatican State.

Dr. Diego Pozza, Director of the Studio di Andrologia e di Chirurgia Andrologica of Rome has organized the International Meetings of Andrology since 1989. The meetings are normally held in Rome and Milan in the first week of June and are dedicated to a specific topic to give the participants opportunity for discussion. This year, the Meeting was dedicated to Peyronie's disease and other conditions with acquired fibrosis of the penis.

The first session, chaired by Prof. Isidori of Rome, reviewed the incidence, pathogenesis and histology of Peyronie's disease. Prof. Pryor of London cited the latest publications regarding the disease and Prof. Tellaloglu of Istanbul reported the incidence of the disease (0.4%) among the urological patients of Turkey. Similar data were obtained in a cooperative study of IGUAS (International Group of Urology, Andrology and Sexology) performed in Italy, Spain and Portugal as reported by Dr. Pozza. Prof. Gentile of Rome reported his findings on the role of growth factors and cellular matrix in the development of the disease, noting common aspects with the collagen modification found in CVOD. The immunological factors that could be at the basis of the collagen modification were noted by Dr. Colpi of Milan. Results in diabetic patients were presented by Dr. Nale of Belgrade.

The session dedicated to diagnosis, chaired by Dr. Papp of Budapest, confirmed the utility of the usual diagnostic investigations in distinguishing the acute from the stable phase. Sonography and NMR remain the best diagnostic tools for investigating Peyronie's disease as outlined by Dr. Andresen of Berlin, and Dr. Shabsigh of New York. Dr. Rossello Barbara of Palma de Mallorca reported his initial data concerning the use of Digital Inflection Rigidometry (DIR) in the diagnosis of erectile failure often associated with Peyronie's disease.

Different types of treatment were discussed with the help of Prof. Micali of Rome and Prof. Tellaloglu who reported on the effect of colchicine on the consistency of the plaques after treatment periods of three months. Dr. Pomerol of Barcelona did not observe any improvement of the disease with orgotein. Dr. Di Luigi of Rome compared various treatments such as timopentine, vitamin E, nimesulide, ionophoresis and laser waves or the use of verapamil with similar uncertain effects. The use of tamoxifen was reported by Dr. Papp.
One of the most interesting sessions, chaired by Prof. Menchini Fabris of Pisa, was dedicated to the use of intracavernous injections of vaso-active drugs in patients with Peyronie's disease. Dr. Pozza summarized his long experience both with papaverine and prostaglandin E1 and similar data were reported by Dr. Shabsigh of New York, Dr. Canale and Dr. Rossi of Pisa using a new vaso-active mixture.

A broad ranging session dedicated to the surgical treatment of Peyronie's disease was chaired by Dr. Carrion of Miami and Prof. Pryor. Dr. Wagenknecht of Hamburg reported his experience on various types of surgical treatments. An interesting part of the session was dedicated to the lectures and discussion on various types of plaque surgery as outlined by Dr. J.C. Speranza of Buenos Aires (fascia temporalis), H. Carrion (venous patch), S. Boyd of Las Angeles (dermis, venous of temporalis fascia), E. Austoni of Milan (dermis), Dr. G. Galek of Bialystok (prepuce). Prof. J. Pryor chaired a lively discussion on the problem of cutting or excising the plaque and how to cover it. A similar interesting discussion took place on the subject of penile prosthetic surgery. After the lectures of S. Boyd, H. Carrion, L. Subrini of Paris, J. Pereira de Silva of Lisbon, the discussion centered on the necessity of improving the straightening of the penis with various techniques.

The last session chaired by Dr. Yachia of Tel Aviv, covered the problems of other conditions with acquired fibrosis of the penis with urethral strictures and micturition problems. Dr. Yachia explained his technique of Uracoil implant, and discussed the various techniques of correcting a bent penis with the various corporoplastic techniques such as Kelami's, Yachia's and Ebbehoi's. Dr. Amar of Paris reported his good series on corporoplasty. Lectures and posters were presented by more than 48 lecturers, many of them coming from eastern European countries such as Croatia, Yugoslavia, Poland, Hungary, Russia, Bulgaria, Ukraine, North Cyprus. It was another opportunity for a useful interaction between Eastern and Western Andrology and an opportunity for all participants to acquire up-to-date information about the old dilemma of Peyronie's disease. The next International Meeting of Andrology in 1997 will permit another cultural exchange on a new andrological topic.

Further information can be obtained from Diego Pozza, Studio di Andrologia e di Chirurgia Androlgica., via Flaminia Nuova, 280, 00191 Rome, Italy, Fax: (+39 6) 363 010 88.

Diego Pozza and Mariangela Pozza, Italy